Potential therapy for severe insulin resistance
نویسندگان
چکیده
منابع مشابه
Molecular genetics of severe insulin resistance.
Leprechaunism and type A diabetes represent inborn errors of insulin resistance whose phenotypes suggested causation by mutations in the insulin receptor gene. Cells cultured from patients with leprechaunism specifically lacked high-affinity insulin binding. Partial but different degrees of impairment were observed in cells cultured from first-degree relatives. Different mutations in the insuli...
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Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1000 words (typed double-spaced) in length and may be subject to editing or abridgment. To the Editor: Ruggenenti et al 1 report that oral administration of acetyl-L-carnitine results in a substantial, sustained, and simultaneous improvement in insulin sensitivity and blood pressure in insulin-resista...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2017
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2017.15